clickchemistry相关论文
开发了一种Ag-Cu双金属负载的胺基石墨烯催化剂用于1,2,3-三唑类化合物的合成.利用各种技术对催化剂进行了表征,催化剂活性测试表......
Natural killer cell-derived extracellular vesicle significantly enhanced adoptive T cell therapy aga
Insufficient tumor tropism,MHC class Ⅰ molecules (MHC-Ⅰ) defects of tumor cells,and immunosuppressive tumor micro-envi......
Since the sulfur(Ⅵ) fluoride exchange reaction (SuFEx) was introduced by Sharpless and co-workers in 2014,this new-gene......
This review reports our recent work on developing polymer synthesis methods based on a self-accelerating double-strain-p......
Quantum dots (QDs) have shown great promise as fluorescent nanoprobes in bioanalysis and bioimaging due to their size-an......
Multifunctional cystine-installed clickable micelles for efficient drug delivery and magnetic resona
Multifunctional polymeric nanocarriers that integrate various desired functions have emerged as the next generation of n......
Cell specific doxorubicin delivery through the temperature responsive lipopolymer nanocarriers engin
Recently,stimuli-responsive nanocarriers have obtained more attention for the targeted and controlled delivery of therap......
Preparation of Poly(ε-Caprolactone)/Attapulgite Nanocomposites via a Combination of Ring-Opening Pol
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Controlled cycloaddition reactions mediated by noncovalent interactions have been applied in syntheses,especially in org......
Boronic acid-functionalized iron oxide magnetic nanoparticles via distillation-precipitation polymer
Objective Glycosylation,as one of the most ubiquitous and complicated posttranslational modifications of proteins,plays ......
Water-soluble polymers such as PEG and its analogues have been widely used to modify proteins.Water-soluble conjugated p......
The combination of chemotherapeutic agents with gene therapy offers a great chance for cancer treatment.In this work, qu......
Clofazimine (CLF),one of the Riminophenazine compounds,was first identified as riminophenazine inhibitors for Mycobacter......
Enrichment of GalNAz labled-glycoproteins by Novel Disulfideand Terminal Alkyne-modified Magnetic Be
Glycosylation is one of the most significant and widespread posttranslational modification of proteins.The change of gly......
We develop a generalized,quantitative chemoproteomic platform that can be broadly applicable to the analyses of biorthog......
Three Novel Porphyrin-Covalently Functionalized Single-Walled Carbon Nanotubes:Synthesis and Enhance
As a powerful means to form new functional materials,carbon nanotubes decorated with specific organic molecules have att......
First Discovery of Novel 3-Hydroxy-quinazoline-2,4(1H,3H)-diones as Specific Anti-Vaccinia and Adeno
The construction of a novel series of 1,2,3-triazolyl 3-hydroxy-quinazoline-2,4(1H,3H)-diones utilizing Cu(I)-catalyzed ......
Polysaccharides are ubiquitous in Nature,building up from various living species like plants,micro-organisms ormammals.T......
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Expansion microscopy(ExM)improves the resolution of fluorescence microscopy though physically magnification of biologica......
Large-scale quantification of protein O-linked β-N-acetylglucosamine(O-GlcNAc)modification in a site-specific manner re......
Lignin Meets Click Chemistry:Towards the Functionalization of Bio-based Adsorbent for Selective Remo
Bio-based adsorbents,in particular lignin,have received wide attention recently because of their natural abundance and t......
Synthesis of Silica-based Mixed-mode Weak Cation-exchange Sorbent by Cu(Ⅰ)-catalyzed “Click Reaction
Solid-phase extraction (SPE) has been widely used to purify and enrich analytes of interest from complex samples.Among v......
Base on click chemistry and DNAzyme1,2,we constructed a cupric ion triggered DNA diode by a tandem linkage-cleavage proc......
Transcriptome-wide discovery of coding and noncoding RNA-binding proteins by click chemistry-assiste
Identification of RNA-binding proteins(RBPs)is a prerequisite for understanding the posttranscriptional gene regulation ......
Site-specific incorporation of photocrosslinker and bioorthogonal amino acids into enteric bacterial
Enteric bacterial pathogens are known to effectively pass through the extremely acidic mammalian stomachs and cause infe......
Epidermal growth factor (EGF) receptor is a tyrosine kinase which regulates cell growth and differentiation and is impli......
Measuring the internal pH of living organisms below pH 5 is challenging.Whereas this extreme acidity will render fluores......
Synthesis of polyacrylonitrile fiber-supported poly-(teritiary amine)@Cu as synergistic catalyst for
A novel polymer-supported copper catalyst based on polyacrylonitrile fiber,capable of acting as a synergistic catalyst f......
As we known, RP-HPLC with ODS column is the most popular and efficient chromatographic mode because of the universal sel......
Ethenesulfonyl Fluoride(ESF):A Versatile Sulfur(Ⅵ)Fluoride Exchange(SuFEx)Click Chemistry Hub and Mo
Sulfur(Ⅵ)fluoride exchange(SuFEx)represents the latest and one of the most powerful reactions in click chemistry.SuFEx ......
4-hydroxynonenal(HNE)modified proteins are closely associated with cellular dysfunctions and biological metabolic proces......
Alzheimers disease(AD), the most common dementia in elderly people, is a progressive, neurodegenerative disorder of the ......
目的:制备一种针对整合素αM(CD11b)受体的预定位分子探针n 68Ga-1，4，7-三氮杂环壬烷-1，4，7-三乙酸-甘氨酸-精氨酸-谷氨酸-精氨酸......
Fluorescent supramolecular nucleoside-based organogels or hydrogels have attracted increasing attention owing to their t......
A cascade linkage-cleavage switch-on system triggered by cupric ion based on click chemistry and DNA
A cascade linkage-cleavage switch-on system triggered by cupric ion was established.The substrate strand was labeled......
A broad range of novel crosslinkers and probes have been designed and synthesized at Conju-Probe for chemical biolog......
Novel photo-responsive ABC 3-miktoarm star copolymers containing polypeptide chain were synthesized via polymer end......
Our laboratory has developed several methods, on the nano-and micro-scale,for analysing ions, biomolecules and mamma......
Involvement of cathepsins in mannose-receptor mediated antigen uptake and processing using a polyman
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锌卤化物建筑群衔接烷基的 bi-heterocycles 从一系列 N-cyanoalkyl-N-alkylimidazolium 卤化物的按反应作为两性离子被获得有钠叠......
Combining Metabolic Alkyne Labeling and Click Chemistry for Secretome Analysis of Serum-Containing C
Main observation and conclusionrnBioorthogonal click chemistry has emerged as a powerful tool for the specific modificat......
High throughput screening towards chemical libraries is the primary way to discover lead compounds in developing innovat......
通过W ong叠氮转化和亲核取代反应,分别合成了叠氮苯丙氨酸、叠氮丙氨酸、苄基叠氮,采用上述叠氮化物与L-炔丙基甘氨酸进行C lick......
依据Web of Science平台下的SCIE数据库中2001-2014年间有关“Click chemistry”的论文数据和文献计量方法,从发表年份、国家、机......
聚丙烯微孔膜在工业上的应用非常广泛，是一种很重要的工业膜材料，但是表面亲水性差导致膜易被污染，而表面改性可以很好地改善膜的抗污......
